Rosacea

Acne rosacea is an inflammatory process that primarily affects the central part of the face. Observed almost exclusively in adults and rarely affects patients younger than 30 years. It is more common in women who have hormonal problems, digestive or nervous Acne rosacea is a type of acne that has little to do with acne vulgaris (common). Hence treatment is different from common acne. Acne rosacea is characterized by the appearance of pink spots on the face that can turn into boils and pimples. Unlike common acne, acne rosacea is not usually occur in people less than 30 years. Those who suffer from acne rosacea are adults, elderly, white-skinned enough and especially women who are reaching the age of menopause. It is very difficult to cure this type of acne completely, but if you can try to achieve significantly reduced. Besides genetic predisposition, some of the most common causes resulting in their appearance are: Prolonged exposure to the sun without protection. It is important to...

NOD2/CARD15 belongs to the N-terminal caspase recruitment domain family of proteins involved in regulating NF-kB activation in response to inflammatory stimuli transduced through Toll-like receptors. Mutations and polymorphisms in the NOD2/CARD15 gene reduce antibacterial responses and are associated with granulomatous inflammatory conditions such as Blau syndrome and early-onset sarcoidosis. The polymorphism R702W (arginine to tryptophan) is strongly associated with susceptibility to Crohn's disease in Caucasian populations. Skin abnormalities (other than cutaneous manifestations of Crohn's disease) have not been previously associated with R702W. We report on a female patient homozygous for R702W who developed granulomatous rosacea at the age of 12 years old. From the occurrence in the context of Crohn associated with R702W, we speculate that granulomatous rosacea may be an entity distinct from other forms of rosacea , which are associated with increased production of antiba...