J Drugs Dermatol. 2009 Feb; 8(2): 120-3Elewski BEA survey of people with rosacea was conducted in 2006 to gain insight into experiences with rosacea therapies and relationships with health care providers. The survey was completed by 2946 participants, of whom 2847 had been diagnosed with rosacea. Participants ranged in age from 20 to 81 years (mean age 50 years). Among those diagnosed with rosacea, 80% agreed that medication prevented their rosacea from worsening. Most respondents currently using prescription medication (82%) did not plan to discontinue its use. Among current users of medication, 46% had switched from a prior agent, usually due to the lack of improvement. Among respondents who previously switched therapies, 84% reported using some formulation of topical metronidazole. Of those respondents who discussed rosacea with their physician, 83% agreed that their physician influences their use of medication; 61% viewed their physician-in most cases a dermatologist-as a partner in managing their rosacea.
Rosacea is a common condition of unknown etiology usually accompanied by gastrointestinal symptoms and favorably responding to the treatment with antibiotics. This study was designed to examine the prevalence of gastric Helicobacter pylori (Hp) infection verified by 13C-UTB-test, CLO, Hp culture and serology (IgG) in patients with rosacea. Gastroduodenoscopy was combined with pentagastrin secretory test and antral and fundic biopsy samples were taken for histological evaluation (the Sydney system). Blood samples were also taken for the determination of plasma gastrin using RIA and plasma interleukin (IL)-8 and tumor necrosis factor alpha (TNFalpha) using ELISA. This study was performed in 60 patients, 31-72 year old, with visible papules and pustules associated with erythema and flushing on the face and on 60 age- and gender-matched patients without any skin diseases but with similar as in rosacea gastrointestinal symptoms but without endoscopic changes in gastroduodenal mucosa (non-...