No rosacea-specific quality-of-life (QOL) instrument exists.
OBJECTIVE:
We sought to develop a validated, reliable rosacea-specific instrument.
METHODS:
From 6 in-depth interviews, we composed 21 rosacea-specific items. These items and Skindex-29 were administered in a validation cohort (n = 59). Internal consistency reliability and reproducibility were measured with Cronbach's coefficient alpha and intraclass correlation coefficient, respectively.
Responsiveness was assessed comparing baseline with 4- to 6-month responses. Construct validity was assessed with principal axes factor analyses. Discriminant validity was examined with an additional 38 patients comparing differences in responsiveness between the rosacea-specific QOL instrument and Skindex.
RESULTS:
Reliability was high (Cronbach's alpha: 0.82-0.97, intraclass correlation coefficient: 0.70-0.95). The rosacea-specific QOL instrument showed preliminary responsiveness for patients with improved disease
"A pilot quality-of-life instrument for acne rosacea"
Nicholson K, Abramova L, Chren MM, Yeung J, Chon SY, Chen SC
J Am Acad Dermatol. 2007 Aug ; 57(2): 213-21 (Hubmed.org)
Highlight :
Treatment Of Rosacea | Acne Rosacea Antibiotic
OBJECTIVE:
We sought to develop a validated, reliable rosacea-specific instrument.
METHODS:
From 6 in-depth interviews, we composed 21 rosacea-specific items. These items and Skindex-29 were administered in a validation cohort (n = 59). Internal consistency reliability and reproducibility were measured with Cronbach's coefficient alpha and intraclass correlation coefficient, respectively.
Responsiveness was assessed comparing baseline with 4- to 6-month responses. Construct validity was assessed with principal axes factor analyses. Discriminant validity was examined with an additional 38 patients comparing differences in responsiveness between the rosacea-specific QOL instrument and Skindex.
RESULTS:
Reliability was high (Cronbach's alpha: 0.82-0.97, intraclass correlation coefficient: 0.70-0.95). The rosacea-specific QOL instrument showed preliminary responsiveness for patients with improved disease
"A pilot quality-of-life instrument for acne rosacea"
Nicholson K, Abramova L, Chren MM, Yeung J, Chon SY, Chen SC
J Am Acad Dermatol. 2007 Aug ; 57(2): 213-21 (Hubmed.org)
Highlight :
Treatment Of Rosacea | Acne Rosacea Antibiotic