J Dermatol Sci. 2009 May 27; Yamasaki K, Gallo RLRosacea is a common and chronic inflammatory skin disease that affects over 10 million Americans. Although the phenotypes of rosacea are clinically heterogeneous, they are all related by the presence of chronic facial skin inflammation. Until recently, the pathophysiology of this disease has been poorly understood and limited to descriptions of factors that exacerbate or improve this disorder. Recent molecular studies suggest that an altered innate immune response is involved in the pathogenesis of the vascular and inflammatory disease seen in patients with rosacea. These findings may help explain the benefits of current treatments and suggest new therapeutic strategies helpful for alleviating this disease. This article discusses the possible molecular mechanisms for the pathogenesis of rosacea from current clinical observations and laboratory research.
Before And After: A Gorgeous Zen Bathroom Remodel " casacullen.com/2009/12/rwd-home-kitchen-redesign-before-and-after almost the same issue during my recent 1960s bath remodel, I house in prime vintage condition and wants to zen " We love when sustainability meets beauty in home renovations. And this Japanese-inspired bathroom remodel in by Weston Miles Architects is a prime example. These before photos show a pleasant enough bathroom with bright color and functional traditional cabinetry, though a small sink space, not-so eco-friendly materials, and dim lighting. This after photo shows an incredible remodel that makes use of traditional materials in a modern aesthetic. The focal point is this Japanese soaking tub that the client wanted, and the room grew around that. The room has been opened up for a step-in shower next to the tub, its warm lichen-green balanced against the natural wood of the tub and wood trim. This beautiful remodel exemplifie...