Rosacea

Curr Opin Otolaryngol Head Neck Surg. 2009 May 21; Brodsky JPURPOSE OF REVIEW: Patients commonly present to the otolaryngologist for management of benign facial lesions. It is important to be able to both recognize these lesions and offer patients the most effective therapies currently available. Advances in the understanding and management of three of the more common benign skin lesions affecting the face will be addressed in this review, with a particular emphasis on the most current therapeutic options for each lesion. RECENT FINDINGS: Actinic keratosis can now be treated with photodynamic therapy or with many topical agents, as alternatives to traditional surgical techniques. Seborrheic keratosis, as well as actinic keratosis and rosacea, are now often treated with laser therapy. In addition, rosacea management now includes nonantimicrobial topical agents, such as azelaic acid, and a wider armamentarium of systemic agents. SUMMARY: An understanding of these options will allow the ...

Int Ophthalmol. 2009 May 23; Jain V, Shome D, Sajnani M, Natarajan SIn order to report fungal keratitis in patients of ocular rosacea, a retrospective review of all cases of fungal keratitis was undertaken. Cases in which ocular rosacea coexisted were identified and included in the study. The clinical course of patients thus identified was studied from the medical records and outcomes were evaluated. A total of three cases of fungal keratitis with coexisting ocular rosacea were identified. All three patients were known cases of acne rosacea with an intermittent, irregular treatment for the same. Previous history of contact lens use, ocular surgery or trauma was not present in any of the cases. Microbiological evaluation revealed Aspergillus flavus as the causative organism in two patients and an unidentified hyaline fungus in the third. Patients received simultaneous therapy for fungal keratitis and ocular rosacea. The ocular surface completely stabilized and the infiltrate resolved i...

J Cosmet Laser Ther. 2009 May 22; 1-3Menezes N, Moreira A, Mota G, Baptista ABackground: Rosacea is a chronic inflammatory eruption of the face that may significantly impair patients' lives, leading to considerable emotional distress and behavioral withdrawal from normal social interactions. The pulsed dye laser is a device that selectively targets oxyhemoglobin with proved efficacy in the treatment of vascular lesions, especially at purpuric doses. Objective: We decided to evaluate the impact of the pulsed dye laser on rosacea patients' quality of life using the Dermatology Life Quality Index (DLQI) score. Methods: Twenty-two patients with erythematotelangiectatic rosacea were enrolled in the study. They were asked to complete a DLQI questionnaire before and after three treatments. Erythema improvement was subjectively evaluated by two investigators who ranked it as equal, better or worse after the three treatments. Results: A statistically significant improvement was observe...

Inflammations of the conjunctiva represent some of the most frequent eye diseases in general and ophthalmologic practice. Etiologically multiple diseases can be identified. A group of infectious conjunctivites contrasts with a very hereogeneous non-infectious group. Neoplastic processes such as low grade epithelial dysplasias and lymphomas may mascarade conjunctivitis. The differentiation of the various clinical pictures may be challenging for the practitioner. This article reviews the methodology of patient history and clinical work up as well as the symptomatology and treatment options for the most important conjunctivites in clinical practice. "Inflammation of the conjunctiva" Ther Umsch. 2009 Mar; 66(3): 153-61Meyer P, Messerli J (Hubmed.org) Highlight : Treatment Of Rosacea | Acne Rosacea Antibiotic

Rhinophyma is an irregular and progressive nasal hypertrophy, due to hyperplasia and fibrosis of the sebaceous glands and surrounding soft tissues. Its etiology is unknown. Its psychosocial, functional, and esthetic consequences may be severe. It is rare in the black African population. We present a case of glandular rhinophyma in a 70-year-old black male patient. OBSERVATION: A 70-year-old male patient consulted for nasal tumors. These lesions had appeared 11 years before, after rosacea acne . The patient had no specific history, no alcohol addiction nor any particular treatment. The nose was voluminous. The tumors were located on the left nostril ala, the tip of the nose, and the tip and right nostril ala junction. The size of the pediculated lesions was variable. They covered most of the nostril opening and upper lip. Pressure forced out whitish, pasty, and fetid sebum. The lesions were an obstacle to nasal ventilation and feeding. This glandular rhinophyma was responsible for a sev...

Surv Ophthalmol. 2009 May-Jun; 54(3): 321-38Donnenfeld E, Pflugfelder SCCyclosporine has been used successfully as a systemic immunomodulator for more than two decades, and numerous studies have investigated its mechanisms of action. In 2003 an ophthalmic formulation, cyclosporine 0.05% ophthalmic emulsion, was approved by the FDA to treat dry eye disease. Topical cyclosporine emulsion has also been investigated for treatment of other ocular surface disorders that may have an immune-based inflammatory component. In these trials, cyclosporine 0.05% ophthalmic emulsion has shown efficacy for management of posterior blepharitis, ocular rosacea, post-LASIK dry eye, contact lens intolerance, atopic keratoconjunctivitis, graft-versus-host disease, and herpetic stromal keratitis. As these disorders are often refractory to other available treatments, ophthalmic cyclosporine is a welcome nontoxic adjunct or replacement to potentially toxic topical or systemic immunosuppressive therapies.

Skin Therapy Lett. 2009 Feb; 14(2): 1-3Gooderham MMany options exist for the treatment of rosacea, including topical and systemic therapies, laser and light-based therapies, and surgical procedures. A classification system for rosacea identifies 4 subtypes (i.e., erythematotelangiectatic, papulopustular, phymatous, and ocular), which may help guide therapeutic decision-making. The goals of therapy include reduction of papules, pustules, erythema, physical discomfort, and an improvement in quality of life. Standard topical treatment agents include metronidazole, azelaic acid, and sodium sulfacetamide-sulfur. Second line therapies include benzoyl peroxide, clindamycin, calcineurin inhibitors, and permethrin.