Skip to main content

Iron status with particular consideration of soluble transferrin receptors in children

Role of Helicobacter pylori infection in chronic gastritis and gastric and/or duodenal ulcers is well known.

Simultaneously there are some articles in literature considering H. pylori as a cause of extra-gastrointestinal illnesses such as atopic dermatitis, chronic urticaria or acne rosacea, hypotrophy, Schoenlein-Henoch disease, atherosclerosis or hypochromic anaemia.

The aim of the study. was to asses iron status in aspect of plasmatic transferrin receptors concentration among children and youth with chronic gastritis with or without Helicobacter pylori infection.

MATERIALS AND METHODS:
Forty one patients were included as a study group. Range of age was 9-18 years. All patients were diagnosed due to chronic abdominal pains. There were 13 males and 28 females. Blood was collected from every patient for blood cell count, iron, transferrin and transferrin receptors concentration (sTfR) assessment before endoscopy of upper gastrointestinal tract.

RESULTS:
Concentration of sTfR was higher than age norm among 29 (71%) of patients. Among patients with higher level of sTfR 20 (69%) had normal haemoglobin concentration and in this group 10 patients had H. pylori infection.

During analysis of 12 patients with nornal level of sTfR normal haemoglobin concentration was found and among five of them H. pylori infection was stated. Among 21 patients without H. pylori infection 14 had normal level of sTfR and 7 had higher level of sTfR which means that 33% had hidden iron deficiency (involuntary of normal Hb concentrations).

Among 15 of 20 patients with H. pylori infection level of sTfR was higher which means that 75% patients with infection had hidden iron deficiency (involuntary of normal Hb concentrations).

CONCLUSION:
Level of plasmatic transferrin receptors can be good and sensitive indicator of iron deficiency and can be helpful in differential diagnosis of hypochromic anaemia and anaemia caused by chronic illness including chronic gastritis with Helicobacter pylori infection.


"Iron status with particular consideration of soluble transferrin receptors in children and youth with gastritis, with or without Helicobacter pylori infection"
Mierzwa G, Augustyńska B, Czerwionka-Szaflarska M, Tyrakowski T
Pol Merkur Lekarski. 2006 Sep ; 21(123): 235-8 (Hubmed.org)




Highlight :
Rosacea Skin Treatment | Acne Rosacea Antibiotic | Acne Rosacea | Prescription Rosacea Creams

Popular posts from this blog

Before And After: A Gorgeous Zen Bathroom Remodel

Before And After: A Gorgeous Zen Bathroom Remodel " casacullen.com/2009/12/rwd-home-kitchen-redesign-before-and-after almost the same issue during my recent 1960s bath remodel, I house in prime vintage condition and wants to zen " We love when sustainability meets beauty in home renovations. And this Japanese-inspired bathroom remodel in by Weston Miles Architects is a prime example. These before photos show a pleasant enough bathroom with bright color and functional traditional cabinetry, though a small sink space, not-so eco-friendly materials, and dim lighting. This after photo shows an incredible remodel that makes use of traditional materials in a modern aesthetic. The focal point is this Japanese soaking tub that the client wanted, and the room grew around that. The room has been opened up for a step-in shower next to the tub, its warm lichen-green balanced against the natural wood of the tub and wood trim. This beautiful remodel exemplifie...

Prevalence Of And Associated Factors For Dry Eye In A Spanish adult population

To estimate the prevalence of dry eye and to investigate its relationship with lifestyle and systemic factors in a general adult population in north-western Spain. METHODS: A dry eye questionnaire was administered and objective tests were performed in 654 individuals [mean age (Standard deviation): 63.6 (14.4) years, range: 40-96, 37.2% males]. Subjects were considered symptomatic when one or more of the symptoms of the questionnaire were present often or all the time. Schirmer test or= 3 and fluorescein staining >or= 1 were considered indicative of signs. Dry eye was defined as the simultaneous presence of symptoms and at least one sign. A design based analysis was performed and all calculations were weighted to give unbiased estimates. RESULTS: Dry eye prevalence was 11.0% (95%confidence interval [CI] 8.6-13.3). Dry eye was found to be more frequent in women (11.9%, 95%CI 8.8-15.1) than in men (9.0%, 95%CI 5.3-12.6), and was significantly associated with aging (p autoimmune diseas...

Enhanced Skin Blood Flow And Sensitivity to Noxious Heat Stimuliin papulopustular rosacea

Although patients with rosacea often complain of increased skin sensitivity, there has been no quantitative sensory testing of this phenomenon. Furthermore, cutaneous blood flow in these patients has not been assessed using state-of-the-art laser Doppler imaging (LDI). OBJECTIVES: To assess heat pain thresholds and skin blood flow using quantitative thermal sensory testing and LDI in patients with untreated rosacea . METHODS: Of the total 24 subjects enrolled, 8 had papulopustular rosacea (PPR), 8 had erythematotelangiectatic rosacea (ETR) and 8 were control subjects. Subjective burning perception, heat pain threshold, skin blood flow, and skin temperature was assessed in all subjects. In the ETR and PPR groups, two areas were compared: affected and nonaffected. RESULTS: Heat pain thresholds of areas affected by rosacea were lower than those of nonaffected areas. In addition, subjective burning perception was increased in rosacea patients when compared with control subjects. Altho...