Skip to main content

Local corticosteroid therapy in dermatology

The introduction of dermocorticosteroids (corticosteroids for topical application) has revolutionized management of many skin diseases. Depending on their antiinflammatory action, these products can be classed into four levels of action. Dermocorticosteroids have antiinflammatory, vasoconstrictor, antiproliferative, antisynthetic and immunosuppressive actions.

SKIN PENETRATION:
Penetration depends on the intrinsic characteristics of the drug, but also on many other factors including the nature of the excipient, additives, occlusion, localization, nature of the treated skin disease, and patient age. There is a reservoir effect, explaining why a single application is effective for dermatoses with a normal keratin layer.

INDICATIONS AND CONTRAINDICATIONS:
Dermocorticosteroids can be indicated in numerous inflammatory skin diseases (psoriasis, eczema ...). They are formally contraindicated in case of skin infections, diaper rash, acne and rosacea. Contact allergies have been reported.

IN PRACTICE:
The choice of a dermatocorticosteroid depends on the suspected sensitivity of the disease to treat, its degree of extension, and its localization as well as the patient's age and the planned duration of treatment. Cremes provide good cosmetic satisfaction. The number of tubes to be used must be strictly controlled. Occlusion is indicated in case of palmo-plantar or the scalp involvement.


"Local corticosteroid therapy in dermatology
Chosidow O, Lebrun-Vignes B, Bourgault-Villada I
Presse Med. 1999 Nov 27; 28(37): 2050-6 (Hubmed.org)



Highlight :
Treatment Of Rosacea | Acne Rosacea Antibiotic | Acne Rosacea | Rosacea Creams

Popular posts from this blog

1971 Innocenti Mini Cooper

1971 Innocenti Mini Cooper " An original Austin Mini Cooper. Not that strange, except I'm 6'4" and 260lbs. Would look kinda funny gettin in and out. _____ " Search Suggestion mk1forum net • view topic early navy blue 1275 gt seats Austin Cooper 998 Mk II 1969 Austin Mini Clubman 1970 Morris Mini Clubman 1275 GT 1971 Cooper S mk III replica 1971 Innocenti Cooper 1300 Export 1974 Morris mini 850 1976. http://mk1-forum.net/viewtopic.php?f=8&t=116 innocenti mini cooper flickr photo sharing After 1971 the production of Mini Coopers were continued in license in Italy by Innocenti as the Innocenti Mini Cooper 1300 and in Spain by Authi (Automoviles de Turismo Hispano . http://www.flickr.com/photos/ilmungo/26099568/ austin mini coopers for sale austin mini cooper classifieds In 1971, the 1275 cc Mini Cooper S was discontinued in the UK, leaving the Mini 1275GT as the only sporting Mini on sale for the rest of the decade. Innocenti in Italy . ht...
Read more

Azelaic acid in the treatment of papulopustular rosacea

To evaluate the clinical efficacy of topical 20% azelaic acid cream and 15% azelaic acid gel compared with their respective vehicles and metronidazole gel in the treatment of papulopustular rosacea . DATA SOURCES: Electronic searches of MEDLINE, EMBASE, BIOSIS, and SciSearch through July or August 2004 and the Cochrane Central Register of Controlled Trials through 2004 (issue 3). We performed hand searches of reference lists, conference proceedings, and clinical trial databases. Experts in rosacea and azelaic acid were contacted. STUDY SELECTION: Randomized controlled trials involving topical azelaic acid (cream or gel) for the treatment of rosacea compared with placebo or other topical treatments. Two authors independently examined the studies identified by the searches. Ten studies were identified, of which 5 were included (873 patients). DATA EXTRACTION: Two authors independently extracted data from the included studies, then jointly assessed methodological quality using a quality a...
Read more

Management of benign skin lesions commonly affecting the face: actinic keratosis, seborrheic keratosis, and rosacea.

Curr Opin Otolaryngol Head Neck Surg. 2009 May 21; Brodsky JPURPOSE OF REVIEW: Patients commonly present to the otolaryngologist for management of benign facial lesions. It is important to be able to both recognize these lesions and offer patients the most effective therapies currently available. Advances in the understanding and management of three of the more common benign skin lesions affecting the face will be addressed in this review, with a particular emphasis on the most current therapeutic options for each lesion. RECENT FINDINGS: Actinic keratosis can now be treated with photodynamic therapy or with many topical agents, as alternatives to traditional surgical techniques. Seborrheic keratosis, as well as actinic keratosis and rosacea, are now often treated with laser therapy. In addition, rosacea management now includes nonantimicrobial topical agents, such as azelaic acid, and a wider armamentarium of systemic agents. SUMMARY: An understanding of these options will allow the ...
Read more